Onnit Alpha Brain Premium Nootropic Brain Supplement Review

Today, we bring you a comprehensive review of the Onnit Alpha Brain, a premium nootropic brain supplement. This particular nootropic stack has garnered considerable global acclaim and has received an endorsement from Joe Rogan. The product asserts its ability to improve focus and cognitive function, ultimately aiding in the successful completion of tasks.

If you’re curious to discover the veracity of these assertions and delve into the effectiveness of this supplement, let’s jump straight into it!

What is Onnit Alpha Brain premium nootropic brain supplement?


Alpha Brain is a flagship cognitive enhancement product offered by Onnit. This supplement incorporates a blend of vitamins, herbs, and amino acids specifically designed to improve cognitive function and prolong “flow states,” characterized by heightened focus and productivity. One notable aspect that distinguishes Alpha Brain from many other brain booster supplements is the support it has received from scientific research [1].

Since its introduction in 2011, Alpha Brain has gained considerable popularity, with customers purchasing up to 1 million bottles. Its success can be attributed, in part, to the endorsement and promotion by Joe Rogan, a well-known podcaster, comedian, and part-owner of Onnit.

To further examine the efficacy of Alpha Brain and determine whether it is a worthwhile supplement to consider, let us continue our review and delve deeper into its mechanisms of action.

Onnit Alpha Brain premium nootropic brain supplement ingredients

The formula of Alpha Brain includes 11 active ingredients, with many having promising research to guarantee their claims. It separates the ingredients into three unique blends to address different phases of cognitive functioning.

So, to see what works in this product and what might be dead weight, let’s take a closer look at what is inside every capsule.


Vitamin B6 – 10 mg

Vitamin B6 is a commonly-found nutrient in most brain supplements. It helps produce necessary coenzymes in hundreds of reactions in the body, including the metabolism of glucose, amino acids, and lipids. Also, it plays a vital role in synthesizing neurotransmitters like dopamine, epinephrine, melatonin, serotonin, GABA, and norepinephrine. Getting enough vitamin B6 might maintain high energy levels during the day.

Onnit Flow Blend – 650 mg

This blend includes three potent ingredients that might stimulate the brain’s production of alpha waves. These waves can make you feel relaxed and calm by improving mental coordination, concentration, and alertness.

  • L-Tyrosine is an essential amino acid that promotes cognition during intense stressors and boosts memory and well-being. It is especially helpful for those who suffer from stress.
  • L-Theanine is another essential amino acid, found in green tea leaves. It works as a relaxing agent to lower stress and enhance alertness. Also, it helps clear brain fog and restrains the side effects of caffeine.
  • Oat straw extract is often used as an anti-anxiety supplement to enhance cognitive abilities and mood [2].
  • Phosphatidylserine is a natural fat that can protect your brain cells, transfer messages between the cells, and keep your brain and memory sharp.

Cat’s Claw Extract – 350 mg

It is a plant native to the Amazon rainforest and has long been used in traditional medicine for many purposes. Recently, research has also shown that it might be a potent nootropic to hinder the formation of beta-amyloid plaques in the brain; such plaques have been assumed as a cause of Alzheimer’s disease [3].

Onnit Focus Blend – 240 mg

This blend might help produce and maintain acetylcholine in the brain. It includes:

  • Alpha GPC is a choline-containing compound that increases the release of acetylcholine, a natural chemical in the nervous system. Acetylcholine is often used to support cognitive functions, including promoting focus and mental performance.
  • Bacopa Monnieri is an adaptogen herb to promote cognition and memory after 6-12 weeks of regular use. The benefits are more noticeable in older people with mild memory decline [4].
  • Huperzine A works as an antioxidant in protecting mitochondrial health to maintain the brain functioning at its optimal. Although it does not increase acetylcholine directly like Alpha GPC, it does hinder the enzyme acetylcholinesterase to let acetylcholine stay well in the brain.

Onnit Fuel Blend – 60 mg

The last blend is used to allow your brain to operate on all cylinders, thereby keeping things running well for an extensive amount of time.

  • L-Leucine is another essential amino acid that plays a vital part in synthesizing muscle protein and is quite popular among bodybuilders and workout enthusiasts. Since it has no nootropic effects, we have no idea why Onnit has put it in this brain supplement.
  • Pterostilbene is a synthetic form of resveratrol that can cross the blood-brain barrier to support different aspects of brain functioning.


How does Onnit Alpha Brain premium nootropic brain supplement work?

The manufacturer of Alpha Brain claims that its product might improve the “flow state” or the point where you are in a non-distracted state of consciousness. In other words, it gains an optimal level of consciousness where it can neglect background noise and other distractions and concentrate on the task.

From the ingredient profile above, it is easy to notice that many do support focus and concentration. There is the structure of promoting alpha wave frequency and creating more neurotransmitters. That means your brain might perform at the best level to surpass what you do.

To determine how well Alpha Brain works, the manufacturer revealed its study. It showed that taking this product gave a remarkable enhancement on tasks of executive functioning and verbal processing [5].

Taking two capsules daily, preferably with a light meal, is suggested for enhancing brain and nerve cell stability. Pregnant or nursing women, children under 18, and those who are on medication or have a medical condition should consult with a doctor before taking it.

The manufacturer states that you might experience results after taking Alpha Brain for as little as 2 hours. But some might feel the effects between 30 minutes to an hour. Also, you need to take it for an extended period (for at least 6 weeks) to optimize the effects. And do not forget that every individual is different and might experience the results differently.

Remember that Onnit Alpha Brain is a dietary supplement, not a drug. And its ingredients are sourced from natural sources, so it is safe and harmless when taken in the suggested dosages. But remember that how your body reacts to the product will depend on many factors like age, overall health, genetic factors, pre-existing conditions, and whether or not you are taking any medication.

There are some side effects associated with large doses. So, watch out for symptoms like headaches, stomach pain, vomiting, insomnia, and anxiety. And if you experience any effect, stop using Alpha Brain and seek medical attention instantly.


Pros and Cons


  • This supplement enhances memory and cognitive function.
  • It gives an all-natural nootropic formula.
  • It is caffeine-free, dairy-free, gluten-free, nut-free, paleo-friendly, and keto-friendly.
  • It has some unique ingredients, like Cat’s Claw and Oat Straw.
  • It delivers an instant effect.
  • It is backed by clinical studies.
  • It offers a 90-day money-back guarantee.


  • This product is more expensive than the others.
  • It only includes vitamin B6.
  • There is no serving size information for most components.

Manufacturing quality

Onnit brand was established in 2010 by Aubrey Marcus. Since he has a background as an athlete, he aimed to make a company that helps customers attain their fullest potential. Alpha Brain was launched in 2011 and has soon become its flagship nootropic.

Alpha Brain now has testimonials from scientists and athletes to prove that it works to boost focus, memory, and cognitive function.


Where can I purchase Onnit Alpha Brain premium nootropic brain supplement?

Ordering from the official Onnit website is one of the best ways to get Alpha Brain for international and U.S. customers. A bottle containing 90 capsules sells for $79.95. This is a premium price tag, but if you subscribe to get a continuous supply, the price is only $67.96.

Also, you can buy Alpha Brain online via Amazon or other supplement stores if you are a loyal customer here.


To sum up

Onnit Alpha Brain might be worth trying if you want a stimulant-free and high-quality nootropic brain supplement. This is especially suitable if you are sensitive to caffeine and need to avoid a jittery effect. Although every customer has a slightly different experience, it appears safe for most. And always ask your medical provider before taking any supplement.

But in case you are still hesitant when it comes to the price tag, you can consult other brain health supplements to find another choice that is more affordable, yet delivers good results.

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